| Company | State | Location | Workers | Notice date |
| Novo Nordisk | NJ | Plainsboro | 811 | 2025-09-01 |
| CyraCom International | AZ | Tucson | 500 | 2025-09-04 |
| PGT Industries, LLC's | FL | HIALEAH, FL, 33018 | 382 | 2025-09-02 |
| Banner Health | CO | Larimer | 351 | 2025-09-04 |
| Perdue Foods | IN | Washington | 293 | 2025-09-03 |
| Weiss Memorial Hospital | IL | Chicago, 4700 N Marine Dr | 289 | 2025-09-05 |
| Salesforce | CA | San Francisco County | 262 | 2025-09-02 |
| LSG Sky Chefs | AZ | Phoenix | 259 | 2025-09-04 |
| Saputo Cheese USA Inc<br/></a><a><em style="font-size:80%; text-decoration:none !important; color:#000">* Layoff start date differs from notice; employer clarified phased layoffs will run Nov–Dec 2025, with exact dates still TBD.</em> | WI | Suamico | 240 | 2025-09-05 |
| Oracle America | CA | San Mateo County | 187 | 2025-09-02 |
| Six Flags Entertainment | CA | Santa Clara County | 184 | 2025-09-04 |
| Essendant | NJ | Cranbury | 171 | 2025-09-01 |
| CyraCom International | FL | TAMPA, FL, 33610 | 150 | 2025-09-04 |
| Essendant | CA | Riverside County | 146 | 2025-09-04 |
| Air Wisconsin Airlines LLC (ATW)<br/></a><a><em style="font-size:80%; text-decoration:none !important; color:#000">* The company provided a separate communication with the breakdown of the number affected at each site.</em> | WI | Appleton | 127 | 2025-09-05 |